Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
| ▸ | PPARD | Q03181 | 2/20 | 0.46 |
| ▸ | PPARA | Q07869 | 2/20 | 0.46 |
| ▸ | HTR1A | P08908 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11103978 | 0.87 | HTR1B (0.62) | HTR1BSMN1; SMN2LMNAMAPK1TSHR | |
| SCHEMBL2711055 | 0.84 | HTR1B (0.59) | HTR1BSMN1; SMN2LMNAMAPK1TSHR | |
| SCHEMBL5929458 | 0.82 | HTR1B (0.71) | HTR1BSMN1; SMN2LMNAMAPK1TSHR | |
| SCHEMBL8956316 | 0.82 | HTR1B (0.57) | HTR1BSMN1; SMN2LMNAMAPK1TSHR | |
| SCHEMBL14956917 | 0.81 | HTR1B (0.61) | HTR1BSMN1; SMN2LMNAMAPK1TSHR | |
| SCHEMBL28306902 | 0.80 | HTR1B (0.59) | HTR1BSMN1; SMN2LMNAMAPK1TSHR | |
| SCHEMBL4743007 | 0.80 | HTR1B (0.59) | HTR1BSMN1; SMN2LMNAMAPK1TSHR | |
| SCHEMBL4740590 | 0.79 | HTR1B (0.62) | HTR1BSMN1; SMN2LMNAMAPK1TSHR | |
| SCHEMBL293595 | 0.79 | HTR1B (0.56) | HTR1BSMN1; SMN2LMNAMAPK1TSHR | |
| SCHEMBL8778574 | 0.79 | MCHR1 (0.45) | HTR1BSMN1; SMN2LMNAMAPK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0574355-B1 | Phosphinyloxy propanaminium inner salt derivatives | CIBA GEIGY AG (CH) | 1997-08-13 | — | — | EP | claimed |
| EP-0574355-A1 | Phosphinyloxy propanaminium inner salt derivatives | SANDOZ LTD. (CH) | 1993-12-15 | — | — | EP | claimed |