Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 8/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 3/20 | 0.49 |
| ▸ | CNR2 | P34972 | 3/20 | 0.49 |
| ▸ | HTR1D | P28221 | 2/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2924471 | 0.90 | CYP2C9 (0.59) | HTR1BCYP2C9CYP1A2CYP2C19CNR1 | |
| SCHEMBL30503960 | 0.90 | CYP2C9 (0.59) | HTR1BCYP2C9CYP1A2CYP2C19CNR1 | |
| SCHEMBL16519470 | 0.86 | CYP2C9 (0.60) | HTR1BCYP2C9CYP1A2CYP2C19CNR1 | |
| SCHEMBL7836734 | 0.84 | CNR1 (0.51) | HTR1BCYP2C9CYP1A2CYP2C19CNR1 | |
| SCHEMBL12968475 | 0.83 | SMN1; SMN2 (0.52) | HTR1BCYP2C9CYP1A2CYP2C19CNR1 | |
| SCHEMBL347409 | 0.82 | CNR1 (0.57) | HTR1BCYP2C9CYP1A2CYP2C19CNR1 | |
| SCHEMBL6938193 | 0.82 | CNR1 (0.57) | HTR1BCYP2C9CYP1A2CYP2C19CNR1 | |
| SCHEMBL2917038 | 0.82 | CNR1 (0.57) | HTR1BCYP2C9CYP1A2CYP2C19CNR1 | |
| SCHEMBL9770405 | 0.82 | CNR1 (0.59) | HTR1BCYP2C9CYP1A2CYP2C19CNR1 | |
| SCHEMBL29502701 | 0.82 | CNR1 (0.59) | HTR1BCYP2C9CYP1A2CYP2C19CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0574355-B1 | Phosphinyloxy propanaminium inner salt derivatives | CIBA GEIGY AG (CH) | 1997-08-13 | — | — | EP | claimed |
| EP-0574355-A1 | Phosphinyloxy propanaminium inner salt derivatives | SANDOZ LTD. (CH) | 1993-12-15 | — | — | EP | claimed |