SCHEMBL8778729

SCHEMBL8778729

CCC(O)S(C)(=O)=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7530917 0.78 TSHR (0.39)
SCHEMBL17324122 0.78 KDM4E (0.31)
SCHEMBL3171361 0.75
SCHEMBL374702 0.75
SCHEMBL7052849 0.75
SCHEMBL10721670 0.73
SCHEMBL1446278 0.73
SCHEMBL3424161 0.73 TSHR (0.35)
Lithium SCHEMBL31186278 0.73
SCHEMBL2696720 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 111 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5300143-A Water soluble dye, sulfone, and amide or cyclic amine XEROX CORPORATION (US) 1994-04-05 US claimed
US-12521442-B2 ASH1L inhibitors and methods of treatment therewith THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2026-01-13 US disclosed
US-12466813-B2 PRC1 inhibitors and methods of treatment therewith THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2025-11-11 US disclosed
US-20250339406-A1 NSD FAMILY INHIBITORS AND METHODS OF TREATMENT THEREWITH THE REGENTS OF THE UNIVERSITY OF MICHIGAN 2025-11-06 US disclosed
EP-4155293-B1 PRC1 INHIBITORS AND METHODS OF TREATMENT THEREWITH UNIV MICHIGAN REGENTS (US) 2025-07-30 EP disclosed
US-12364688-B2 NSD family inhibitors and methods of treatment therewith THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2025-07-22 US disclosed
WO-2025151884-A1 USE OF GLYCOSAMINOGLYCAN SULFATED POLYSACCHARIDES SUCH AS SODIUM PENTOSAN POLYSULFATE IN COMBINATION WITH PERMEATION AGENTS TO TREAT ALZHEIMER'S DISEASE PARSONS C LOWELL (US) 2025-07-17 WO disclosed
US-12285490-B2 ASH1L degraders and methods of treatment therewith THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2025-04-29 US disclosed
US-20250017878-A1 USE OF NADOLOL TO TREAT CHRONIC OBSTRUCTIVE PULMONARY DISEASE BY BLOCKAGE OF THE ARRESTIN-2 PATHWAY CHRONIC AIRWAY THERAPEUTICS LTD (AU) 2025-01-16 US disclosed
EP-3706737-B1 ASH1L INHIBITORS AND METHODS OF TREATMENT THEREWITH UNIV MICHIGAN REGENTS (US) 2025-01-01 EP disclosed
CN-102265447-B Battery electrolyte solution containing aromatic phosphorus compound DOW GLOBAL TECHNOLOGIES INC 2015-05-06 CN disclosed
CN-102639544-B Process for manufacturing phosphate esters from phosphoryl chloride and monoalkyl ethers of glycols or polyglycols DOW GLOBAL TECHNOLOGIES LLC 2015-04-29 CN disclosed
CN-102823051-B Battery electrolyte solution containing phosphorus-sulfur compound DOW GLOBAL TECHNOLOGIES INC 2015-04-01 CN disclosed
CN-104334539-A Salt of bicyclic aromatic anions for li-ion batteries ARKEMA FRANCE 2015-02-04 CN disclosed
CN-104334538-A Salts of bicyclic aromatic anions for lithium ion batteries ARKEMA FRANCE 2015-02-04 CN disclosed
WO-2014164543-A1 COMPOSITIONS COMPRISING THIENOPYRIMIDINE AND THIENOPYRIDINE COMPOUNDS AND METHODS OF USE THEREOF THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2014-10-09 WO disclosed
US-20140275070-A1 COMPOSITIONS COMPRISING THIENOPYRIMIDINE AND THIENOPYRIDINE COMPOUNDS AND METHODS OF USE THEREOF THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2014-09-18 US disclosed
EP-0602914-B1 Ink compositions for ink jet printing XEROX CORP (US) 1997-11-12 EP disclosed
EP-0602914-A1 Ink compositions for ink jet printing XEROX CORPORATION (US) 1994-06-22 EP disclosed
US-5300143-A Water soluble dye, sulfone, and amide or cyclic amine XEROX CORPORATION (US) 1994-04-05 US disclosed