Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 6/20 | 0.35 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | CTSD | P07339 | 3/20 | 0.32 |
| ▸ | BACE1 | P56817 | 3/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.30 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.30 |
| ▸ | TDP2 | O95551 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6559622 | 0.99 | CNR1 (0.37) | CNR1CNR2HTR2BTMEM97SIGMAR1 | |
| SCHEMBL6024969 | 0.88 | BACE1 (0.37) | CNR1CNR2HTR2BCTSDBACE1 | |
| SCHEMBL6025054 | 0.88 | BACE1 (0.37) | CNR1CNR2HTR2BCTSDBACE1 | |
| Hydrochloric Acid SCHEMBL6561181 | 0.86 | HTR2B (0.46) | CNR1CNR2HTR2BTMEM97SIGMAR1 | |
| SCHEMBL15086547 | 0.79 | TRPV1 (0.41) | CNR1CNR2CTSDBACE1TRPV1 | |
| SCHEMBL3574214 | 0.79 | TRPV1 (0.41) | CNR1CNR2CTSDBACE1TRPV1 | |
| Hydrochloric Acid SCHEMBL23362822 | 0.78 | TRPV1 (0.40) | CNR1CNR2CTSDBACE1TRPV1 | |
| SCHEMBL7479500 | 0.77 | HTR2C (0.42) | CNR1CNR2HTR2BSIGMAR1HTR1A | |
| SCHEMBL3322619 | 0.76 | TRPV1 (0.41) | TRPV1 | |
| Hydrochloric Acid SCHEMBL6561142 | 0.76 | HTR2C (0.41) | CNR1CNR2HTR2BSIGMAR1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0807629-A1 | Sulfonamido substituted chromane derivatives, method for their preparation, their use as medicaments or diagnostic agents aswell as medicaments containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-11-19 | — | — | EP | disclosed |