Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8777283 | 0.86 | CYP1A2 (0.53) | CYP1A2KMT2AABCG2MAPTALDH1A1 | |
| SCHEMBL8777077 | 0.86 | CYP1A2 (0.69) | CYP1A2KMT2AABCG2MAPTALDH1A1 | |
| SCHEMBL3789195 | 0.82 | KDM4E (0.47) | KMT2AMAPTALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL3204572 | 0.82 | CYP1A2 (0.68) | CYP1A2KMT2AOPRK1ABCG2MAPT | |
| SCHEMBL8779050 | 0.80 | MAPT (0.41) | KMT2AMAPTALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL8779053 | 0.80 | PDE10A (0.41) | KMT2AMAPTALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL8779166 | 0.80 | PDE10A (0.41) | CYP1A2KMT2AABCG2MAPTALDH1A1 | |
| SCHEMBL8779034 | 0.80 | KMT2A (0.44) | KMT2AMAPTALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL8776938 | 0.79 | PDE10A (0.51) | CYP1A2KMT2AMAPTALDH1A1TDP1 | |
| SCHEMBL9607579 | 0.79 | CYP1A2 (0.45) | CYP1A2KMT2AABCG2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012069652-A2 | FUNGICIDE MIXTURES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-05-31 | — | — | WO | disclosed |
| US-20120129875-A1 | SUBSTITUTED QUINAZOLINES AS FUNGICIDES | SYNGENTA CROP PROTECTION, LLC (US) | 2012-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120129875-A1 | SUBSTITUTED QUINAZOLINES AS FUNGICIDES | NAT1, NQO2, NOX1 | CYP1A2 18/4885KMT2A 2145/4885OPRK1 4416/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.