Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.38 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.38 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.38 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.38 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.37 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.37 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.37 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.37 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.37 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 2/20 | 0.37 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.35 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17148796 | 0.85 | SLC6A2 (0.37) | SLC6A2SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL2287910 | 0.83 | PTPN1 (0.51) | SLC6A2SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL2287912 | 0.83 | PTPN1 (0.51) | SLC6A2SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL2292205 | 0.83 | PTPN1 (0.51) | SLC6A2SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL12380734 | 0.83 | PTPN1 (0.51) | SLC6A2SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL2292198 | 0.83 | PTPN1 (0.51) | SLC6A2SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL12380733 | 0.83 | PTPN1 (0.51) | SLC6A2SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL2012813 | 0.83 | BCHE (0.40) | SLC6A2SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL2012812 | 0.83 | BCHE (0.40) | SLC6A2SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL2013222 | 0.83 | SLC6A2 (0.38) | SLC6A2SSTR1SSTR2SSTR4SSTR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0787739-A1 | Anti-adhesive piperidine and pyrollidine -carboxylic acids | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-08-06 | — | — | EP | disclosed |