Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RARB | P10826 | 1/20 | 0.51 |
| ▸ | RARG | P13631 | 1/20 | 0.51 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | ESRRG | P62508 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28232672 | 0.85 | HDAC1 (0.53) | HDAC1SRD5A2RAB9AMAPTNPC1 | |
| SCHEMBL28899288 | 0.84 | KCNK9 (0.56) | HDAC1SRD5A2RAB9AMAPTNPC1 | |
| SCHEMBL24534543 | 0.76 | HDAC1 (0.56) | HDAC1SRD5A2RAB9AMAPTNR1H4 | |
| SCHEMBL19240364 | 0.76 | HDAC1 (0.50) | HDAC1SRD5A2RAB9AMAPTNPC1 | |
| SCHEMBL15074379 | 0.76 | TNF (0.46) | HDAC1SRD5A2RAB9AMAPTNPC1 | |
| SCHEMBL10705625 | 0.76 | CA12 (0.48) | HDAC1RAB9AMAPTNPC1POLB | |
| SCHEMBL5690964 | 0.76 | HDAC1 (0.72) | HDAC1SRD5A2RAB9AMAPTNPC1 | |
| SCHEMBL14714003 | 0.75 | HDAC1 (0.48) | HDAC1SRD5A2RAB9AMAPTNPC1 | |
| SCHEMBL4578492 | 0.75 | SRD5A2 (0.57) | HDAC1SRD5A2RAB9AMAPTNPC1 | |
| SCHEMBL12812534 | 0.75 | MAPT (0.44) | RAB9AMAPTNPC1POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0396364-B1 | Copolymers of vinyl carbonate and vinyl carbamate as contact lens material | BAUSCH & LOMB (US) | 1997-06-11 | — | — | EP | claimed |