Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8779888 | 1.00 | APEX1 (0.44) | APEX1 | |
| SCHEMBL499417 | 0.85 | APEX1 (0.44) | APEX1 | |
| SCHEMBL499964 | 0.83 | MEN1 (0.46) | — | |
| SCHEMBL1430689 | 0.83 | MEN1 (0.46) | — | |
| SCHEMBL8779971 | 0.83 | MEN1 (0.46) | — | |
| Hydrochloric Acid SCHEMBL4889627 | 0.82 | MEN1 (0.45) | — | |
| SCHEMBL8779858 | 0.81 | — | — | |
| SCHEMBL8779882 | 0.81 | GGPS1 (0.43) | — | |
| SCHEMBL8779876 | 0.81 | — | — | |
| SCHEMBL1429155 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0539057-B1 | Benzimidazole phosphono-amino acids | AMERICAN HOME PROD (US) | 1997-07-16 | — | — | EP | claimed |
| EP-0539057-A1 | Benzimidazole phosphono-amino acids | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-04-28 | — | — | EP | claimed |
| EP-0539057-B1 | Benzimidazole phosphono-amino acids | AMERICAN HOME PROD (US) | 1997-07-16 | — | — | EP | disclosed |
| EP-0539057-A1 | Benzimidazole phosphono-amino acids | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-04-28 | — | — | EP | disclosed |
| US-5124319-A | Administering for treatment of neuropathological disorders induced by overstimulation of excitatory amino acid receptors | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-06-23 | — | — | US | disclosed |