Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 4/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.36 |
| ▸ | TLR2 | O60603 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | HTR2B | P41595 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | GBA1 | P04062 | 1/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8550985 | 0.89 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3ADRB1HTR2A | |
| SCHEMBL2721007 | 0.84 | SLC6A2 (0.52) | SLC6A2SLC6A4SLC6A3ADRB1HTR2A | |
| SCHEMBL27683903 | 0.81 | HTR2B (0.41) | SLC6A2SLC6A4SLC6A3HTR2AHTR2C | |
| SCHEMBL644545 | 0.77 | SLC6A2 (0.54) | SLC6A2SLC6A4SLC6A3ADRB1HTR2A | |
| Bromide SCHEMBL27797303 | 0.76 | SLC6A2 (0.53) | SLC6A2SLC6A4SLC6A3ADRB1HTR2A | |
| Hydrochloric Acid SCHEMBL5793498 | 0.76 | SLC6A2 (0.53) | SLC6A2SLC6A4SLC6A3ADRB1HTR2A | |
| SCHEMBL5037533 | 0.76 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3ADRB1HTR2A | |
| SCHEMBL6220026 | 0.76 | SLC6A2 (0.61) | SLC6A2SLC6A4SLC6A3ADRB1GRM2 | |
| SCHEMBL7800662 | 0.74 | SLC6A2 (0.62) | SLC6A2SLC6A4SLC6A3ADRB1CYP2D6 | |
| SCHEMBL28276488 | 0.73 | SLC6A2 (0.47) | SLC6A2SLC6A4SLC6A3ADRB1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0788511-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-08-13 | — | — | EP | disclosed |