⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10625444 | 0.96 | — | — | |
| SCHEMBL923939 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL11424967 | 0.77 | — | — | |
| Fluoride SCHEMBL29188541 | 0.75 | — | — | |
| SCHEMBL6429188 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL10486811 | 0.75 | — | — | |
| SCHEMBL27936096 | 0.75 | — | — | |
| SCHEMBL19353622 | 0.75 | — | — | |
| SCHEMBL10939144 | 0.75 | — | — | |
| SCHEMBL11382776 | 0.75 | KDM4E (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4160779-A | Process for the production of methylaminomethylphosphonic acid and its salts | CIBA-GEIGY CORPORATION (US) | 1979-07-10 | — | — | US | claimed |
| EP-0435059-B1 | Retroviral protease inhibitors | HOECHST AG (DE) | 1997-11-05 | — | — | EP | disclosed |
| US-5629431-A | Inhibitors of retroviral proteases | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-05-13 | — | — | US | disclosed |
| US-5510504-A | Process for the preparation of derivatives of bis(amino-methyl) phosphinic acid | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-04-23 | — | — | US | disclosed |
| EP-0435059-A1 | Retroviral protease inhibitors | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-07-03 | — | — | EP | disclosed |
| US-4171969-A | Bis(aminomethyl)phosphinic acid | CIBA-GEIGY CORPORATION (US) | 1979-10-23 | — | — | US | disclosed |
| US-4160779-A | Process for the production of methylaminomethylphosphonic acid and its salts | CIBA-GEIGY CORPORATION (US) | 1979-07-10 | — | — | US | disclosed |
| US-4136154-A | OXIDATION RESISTANCE, ZINC, ALUMINUM, OR CALCIUM SALT OF A PHOSPHINIC ACID | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-01-23 | — | — | US | disclosed |
| US-4016222-A | Unsaturated phosphorus compounds | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-04-05 | — | — | US | disclosed |