Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 | Q99808 | 2/20 | 0.79 |
| ▸ | TP53 | P04637 | 2/20 | 0.75 |
| ▸ | LMNA | P02545 | 1/20 | 0.75 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.75 |
| ▸ | TSHR | P16473 | 1/20 | 0.75 |
| ▸ | HTT | P42858 | 1/20 | 0.75 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.75 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.72 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.72 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.71 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.71 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14713466 | 1.00 | SLC29A1 (0.79) | SLC29A1TP53LMNAALOX15TSHR | |
| SCHEMBL19225603 | 1.00 | SLC29A1 (0.79) | SLC29A1TP53LMNAALOX15TSHR | |
| SCHEMBL6758546 | 1.00 | SLC29A1 (0.79) | SLC29A1TP53LMNAALOX15TSHR | |
| SCHEMBL13966409 | 1.00 | SLC29A1 (0.79) | SLC29A1TP53LMNAALOX15TSHR | |
| SCHEMBL14713238 | 0.91 | SLC29A1 (0.86) | SLC29A1TP53LMNAALOX15TSHR | |
| SCHEMBL20626332 | 0.91 | SLC29A1 (0.86) | SLC29A1TP53LMNAALOX15TSHR | |
| SCHEMBL6758909 | 0.91 | SLC29A1 (0.86) | SLC29A1TP53LMNAALOX15TSHR | |
| SCHEMBL29634977 | 0.91 | TP53 (0.78) | SLC29A1TP53LMNAALOX15TSHR | |
| SCHEMBL18740390 | 0.91 | TP53 (0.78) | SLC29A1TP53LMNAALOX15TSHR | |
| SCHEMBL31395324 | 0.89 | SLC29A1 (0.70) | SLC29A1LMNAADORA3ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0683789-B1 | N-ALKYL-2-SUBSTITUTED ATP ANALOGUES | ASTRA PHARMA PROD (GB) | 1997-11-05 | — | — | EP | disclosed |
| EP-0253962-B1 | USE OF ADENOSINE DERIVATIVES AS ANTI-DEMENTIA AGENTS | HOECHST JAPAN LIMITED (JP) | 1993-03-24 | — | — | EP | disclosed |