Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 17/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7011089 | 0.87 | NAMPT (0.65) | NAMPT | |
| SCHEMBL6646546 | 0.87 | NAMPT (0.56) | NAMPT | |
| SCHEMBL17195780 | 0.84 | NAMPT (1.00) | NAMPT | |
| SCHEMBL7004700 | 0.83 | MAPT (0.57) | NAMPT | |
| SCHEMBL17184516 | 0.82 | NAMPT (0.91) | NAMPT | |
| SCHEMBL17941988 | 0.82 | NAMPT (0.81) | NAMPT | |
| SCHEMBL17195932 | 0.80 | NAMPT (0.91) | NAMPT | |
| SCHEMBL17942055 | 0.79 | NAMPT (1.00) | NAMPT | |
| SCHEMBL17942068 | 0.78 | NAMPT (0.89) | NAMPT | |
| SCHEMBL17196203 | 0.78 | NAMPT (0.83) | NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0797567-A1 | NOVEL AMINO ACID DERIVATIVES WITH IMPROVED MULTI-DRUG RESISTANCE ACTIVITY | Vertex Pharmaceuticals Incorporated (US) | 1997-10-01 | — | — | EP | disclosed |
| WO-1996015101-A1 | NOVEL AMINO ACID DERIVATIVES WITH IMPROVED MULTI-DRUG RESISTANCE ACTIVITY | VERTEX PHARMACEUTICALS INCORPORATED (US) | 1996-05-23 | — | — | WO | disclosed |