Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 17/20 | 0.38 |
| ▸ | CTSD | P07339 | 1/20 | 0.34 |
| ▸ | NQO2 | P16083 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL891871 | 1.00 | BACE1 (0.38) | BACE1CTSDNQO2 | |
| SCHEMBL892224 | 0.92 | BACE1 (0.48) | BACE1 | |
| SCHEMBL892255 | 0.84 | PDE7A (0.38) | — | |
| SCHEMBL891892 | 0.79 | BACE1 (0.51) | BACE1CTSD | |
| SCHEMBL875232 | 0.68 | BCHE (0.47) | — | |
| SCHEMBL891684 | 0.65 | BACE1 (0.49) | BACE1CTSD | |
| SCHEMBL12747304 | 0.63 | BACE1 (0.82) | BACE1 | |
| SCHEMBL12827639 | 0.62 | BACE1 (0.85) | BACE1 | |
| SCHEMBL12746214 | 0.62 | BACE1 (0.61) | BACE1 | |
| SCHEMBL10209616 | 0.62 | BACE1 (0.70) | BACE1CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012040641-A2 | COMPOUNDS FOR TREATING NEURODEGENERATIVE DISEASES | ARRAY BIOPHARMA INC. (US) | 2012-03-29 | — | — | WO | disclosed |