Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | DAO | P14920 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL64283 | 1.00 | — | — | |
| Hydrogen Sulfide SCHEMBL5894730 | 0.96 | — | — | |
| SCHEMBL29764 | 0.81 | NPC1 (0.52) | MAPTNPC1RAB9ASMN1; SMN2DAO | |
| Acetic Acid SCHEMBL10683356 | 0.80 | DAO (0.61) | MAPTNPC1RAB9ASMN1; SMN2DAO | |
| SCHEMBL12982161 | 0.78 | NPC1 (0.50) | MAPTNPC1RAB9ASMN1; SMN2DAO | |
| SCHEMBL12170048 | 0.78 | NPC1 (0.50) | MAPTNPC1RAB9ASMN1; SMN2DAO | |
| SCHEMBL11997754 | 0.78 | NPC1 (0.50) | MAPTNPC1RAB9ASMN1; SMN2DAO | |
| SCHEMBL120939 | 0.78 | NPC1 (0.50) | MAPTNPC1RAB9ASMN1; SMN2DAO | |
| SCHEMBL12982405 | 0.78 | NPC1 (0.50) | MAPTNPC1RAB9ASMN1; SMN2DAO | |
| SCHEMBL10298258 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0770085-A1 | HETEROAROMATIC DIPHOSPHINES AS CHIRAL LIGANDS | ITALFARMACO SUD S.p.A. (IT) | 1997-05-02 | — | — | EP | disclosed |