Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.60 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CA4 | P22748 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MGLL | Q99685 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CDC25C | P30307 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3118575 | 0.94 | CHRM2 (0.59) | KCNH2CHRM2MEN1KMT2ACA12 | |
| Hydrochloric Acid SCHEMBL11139285 | 0.92 | CHRM2 (0.63) | KCNH2CHRM2MEN1KMT2ACA12 | |
| SCHEMBL7939602 | 0.90 | KCNH2 (0.63) | KCNH2CHRM2MEN1KMT2ACA12 | |
| SCHEMBL11238993 | 0.89 | KCNH2 (0.63) | KCNH2CHRM2MEN1KMT2ASIGMAR1 | |
| SCHEMBL9628053 | 0.88 | KCNH2 (0.73) | KCNH2CHRM2MEN1KMT2ACA12 | |
| Hydrochloric Acid SCHEMBL11229997 | 0.88 | KCNH2 (0.62) | KCNH2CHRM2MEN1KMT2ASIGMAR1 | |
| SCHEMBL3116995 | 0.88 | CHRM2 (0.65) | KCNH2CHRM2SIGMAR1HDAC3HDAC1 | |
| SCHEMBL11235448 | 0.88 | KCNH2 (0.66) | KCNH2CHRM2SIGMAR1HDAC3HDAC1 | |
| SCHEMBL11236700 | 0.88 | KCNH2 (0.66) | KCNH2CHRM2SIGMAR1HDAC3HDAC1 | |
| SCHEMBL3122783 | 0.88 | CHRM2 (0.65) | KCNH2CHRM2SIGMAR1HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0697407-B1 | Pyrimidinedione derivatives and antiarrhythmic compositions containing same | MITSUI TOATSU CHEMICALS (JP) | 1997-06-25 | — | — | EP | disclosed |
| EP-0697407-A1 | Pyrimidinedione derivatives and antiarrhythmic compositions containing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-02-21 | — | — | EP | disclosed |