Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | CDK1 | P06493 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10859355 | 0.86 | GAA (0.63) | GAACYP1A2MAPTTP53GLA | |
| SCHEMBL8676026 | 0.86 | GAA (0.63) | GAACYP1A2MAPTTP53GLA | |
| SCHEMBL7800046 | 0.84 | GAA (0.61) | GAACYP1A2MAPTTP53GLA | |
| SCHEMBL8859618 | 0.83 | GAA (0.60) | GAACYP1A2MAPTTP53GLA | |
| SCHEMBL8431787 | 0.83 | CYP1A2 (0.75) | GAACYP1A2MAPTTP53GLA | |
| SCHEMBL9086239 | 0.81 | GAA (0.57) | GAACYP1A2MAPTTP53GLA | |
| SCHEMBL10616100 | 0.80 | GAA (0.60) | GAACYP1A2MAPTTP53GLA | |
| SCHEMBL10616134 | 0.80 | GAA (0.67) | GAACYP1A2MAPTTP53GLA | |
| SCHEMBL28751116 | 0.80 | GAA (0.56) | GAACYP1A2MAPTTP53GLA | |
| SCHEMBL10670178 | 0.79 | GAA (0.77) | GAACYP1A2MAPTTP53GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1100755-C | Aminophenyl ketone derivative and preparation method thereof | AMERICAN CYANIAMID CO (US) | 2003-02-05 | — | — | CN | disclosed |
| CN-1185430-A | Aminophenyl ketone derivative and preparation method thereof | AMERICAN CYANIAMID CO (US) | 1998-06-24 | — | — | CN | disclosed |
| EP-0661275-B1 | 1-alpha-cyclopropyl-alpha-(substituted oxy)-o-tolyl sulfamoyl -3-(4,6-dimethoxy-2-pyrimidinyl)urea herbicidal agents | AMERICAN CYANAMID CO (US) | 1997-06-18 | — | — | EP | disclosed |
| EP-0661275-A1 | 1-alpha-cyclopropyl-alpha-(substituted oxy)-o-tolyl sulfamoyl -3-(4,6-dimethoxy-2-pyrimidinyl)urea herbicidal agents | AMERICAN CYANAMID COMPANY (US) | 1995-07-05 | — | — | EP | disclosed |
| CN-1088910-A | In the preparation crop-selective herbicides as the 4-hydroxyl-2 of intermediate '-nitro n-butyrophenone and tetrahydrochysene-2-(o-nitrophenyl)-2-furans alcohol | AMERICAN CYANAMID CO (US) | 1994-07-06 | — | — | CN | disclosed |