Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 10/20 | 0.41 |
| ▸ | ESR1 | P03372 | 6/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NOS3 | P29474 | 2/20 | 0.34 |
| ▸ | NOS1 | P29475 | 2/20 | 0.34 |
| ▸ | NOS2 | P35228 | 2/20 | 0.34 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10971791 | 1.00 | ESR2 (0.41) | ESR2ESR1CYP2C9CYP3A4SLC18A3 | |
| SCHEMBL10997235 | 0.95 | ESR2 (0.38) | ESR2ESR1CYP2C9CYP3A4SLC18A3 | |
| SCHEMBL10997233 | 0.95 | ESR2 (0.38) | ESR2ESR1CYP2C9CYP3A4SLC18A3 | |
| SCHEMBL11210597 | 0.91 | ESR2 (0.47) | ESR2ESR1CYP2C9CYP3A4CYP2D6 | |
| SCHEMBL11210601 | 0.91 | ESR2 (0.47) | ESR2ESR1CYP2C9CYP3A4CYP2D6 | |
| SCHEMBL10935693 | 0.85 | ESR2 (0.43) | ESR2ESR1CYP2C9CYP3A4CYP2D6 | |
| SCHEMBL10935713 | 0.85 | ESR2 (0.43) | ESR2ESR1CYP2C9CYP3A4CYP2D6 | |
| SCHEMBL10935701 | 0.85 | ESR2 (0.43) | ESR2ESR1CYP2C9CYP3A4CYP2D6 | |
| SCHEMBL11217896 | 0.85 | ESR2 (0.43) | ESR2ESR1CYP2C9CYP3A4CYP2D6 | |
| SCHEMBL10904861 | 0.85 | ESR2 (0.43) | ESR2ESR1CYP2C9CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0126883-B1 | LIQUID CRYSTALLINE CYCLOHEXYLBENZENE DERIVATIVES, THEIR PREPARATION AND THE LIQUID CRYSTAL COMPOSITIONS CONTAINING THEM | Wojskowa Akademia Techniczna im. Jaroslawa Dabrowskiego (PL) | 1987-03-11 | — | — | EP | claimed |
| EP-0126883-A1 | Liquid crystalline cyclohexylbenzene derivatives, their preparation and the liquid crystal compositions containing them | Wojskowa Akademia Techniczna im. Jaroslawa Dabrowskiego (PL) | 1984-12-05 | — | — | EP | claimed |
| JP-57159742-A | — | — | None | — | — | JP | disclosed |
| JP-60146868-A | — | — | None | — | — | JP | disclosed |
| JP-57183730-A | — | — | None | — | — | JP | disclosed |
| JP-58185579-A | — | — | None | — | — | JP | disclosed |
| EP-2619284-B2 | LIQUID CRYSTAL DISPLAYS AND LIQUID CRYSTALLINE MEDIA WITH HOMEOTROPIC ALIGNMENT | MERCK PATENT GMBH (DE) | 2022-12-28 | — | — | EP | disclosed |
| EP-3660130-B1 | LIQUID CRYSTAL DISPLAYS AND LIQUID CRYSTALLINE MEDIA WITH HOMEOTROPIC ALIGNMENT | MERCK PATENT GMBH (DE) | 2021-08-04 | — | — | EP | disclosed |
| US-11015121-B2 | Liquid crystal displays and liquid crystalline media with homeotropic alignment | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2021-05-25 | — | — | US | disclosed |
| EP-3660130-A1 | LIQUID CRYSTAL DISPLAYS AND LIQUID CRYSTALLINE MEDIA WITH HOMEOTROPIC ALIGNMENT | Merck Patent GmbH (DE) | 2020-06-03 | — | — | EP | disclosed |
| US-20190256771-A1 | LIQUID CRYSTAL DISPLAYS AND LIQUID CRYSTALLINE MEDIA WITH HOMEOTROPIC ALIGNMENT | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2019-08-22 | — | — | US | disclosed |
| EP-2619284-A1 | LIQUID CRYSTAL DISPLAYS AND LIQUID CRYSTALLINE MEDIA WITH HOMEOTROPIC ALIGNMENT | Merck Patent GmbH (DE) | 2013-07-31 | — | — | EP | disclosed |
| US-20130182202-A1 | LIQUID CRYSTAL DISPLAYS AND LIQUID CRYSTALLINE MEDIA WITH HOMEOTROPIC ALIGNMENT | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2013-07-18 | — | — | US | disclosed |
| WO-2012038026-A1 | LIQUID CRYSTAL DISPLAYS AND LIQUID CRYSTALLINE MEDIA WITH HOMEOTROPIC ALIGNMENT | MERCK PATENT GMBH (DE) | 2012-03-29 | — | — | WO | disclosed |
| EP-0126883-B1 | LIQUID CRYSTALLINE CYCLOHEXYLBENZENE DERIVATIVES, THEIR PREPARATION AND THE LIQUID CRYSTAL COMPOSITIONS CONTAINING THEM | Wojskowa Akademia Techniczna im. Jaroslawa Dabrowskiego (PL) | 1987-03-11 | — | — | EP | disclosed |
| JP-S60146868-A | 4-SUBSTITUTED PHENYL ISOTHIOCYANATE | CHISSO CORP | 1985-08-02 | — | — | JP | disclosed |
| EP-0126883-A1 | Liquid crystalline cyclohexylbenzene derivatives, their preparation and the liquid crystal compositions containing them | Wojskowa Akademia Techniczna im. Jaroslawa Dabrowskiego (PL) | 1984-12-05 | — | — | EP | disclosed |
| JP-S58185579-A | LIQUID CRYSTAL ESTER COMPOUND | SEIKO EPSON CORP | 1983-10-29 | — | — | JP | disclosed |
| JP-S57183730-A | LIQUID CRYSTAL COMPOUND | SEIKO EPSON CORP | 1982-11-12 | — | — | JP | disclosed |
| JP-S57159742-A | LIQUID CRYSTAL ESTER | SEIKO EPSON CORP | 1982-10-01 | — | — | JP | disclosed |