Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PTPRC | P08575 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8069191 | 0.88 | KDM4E (0.48) | NR4A2FFAR1MAPTMAOBNPC1 | |
| SCHEMBL8782010 | 0.86 | FFAR1 (0.46) | NR4A2FFAR1FFAR4MAPTMAOB | |
| SCHEMBL8782325 | 0.86 | KDM4E (0.48) | NR4A2FFAR1FFAR4MAOAMAOB | |
| SCHEMBL8782264 | 0.85 | NR4A2 (0.50) | NR4A2MRGPRX4MAOAMAOBOPRL1 | |
| SCHEMBL8782235 | 0.83 | FFAR1 (0.47) | FFAR1FFAR4MAPTMAOAMAOB | |
| SCHEMBL9442077 | 0.82 | FFAR4 (0.49) | FFAR1FFAR4MRGPRX4MAOAMAOB | |
| SCHEMBL8782222 | 0.82 | NR4A2 (0.51) | NR4A2FFAR1FFAR4MRGPRX4MAOA | |
| SCHEMBL8782195 | 0.81 | MRGPRX4 (0.72) | MRGPRX4NPC1RAB9ATP53HTT | |
| SCHEMBL8594844 | 0.81 | FFAR1 (0.39) | NR4A2FFAR1FFAR4MRGPRX4MAPT | |
| SCHEMBL8594846 | 0.81 | FFAR1 (0.39) | NR4A2FFAR1FFAR4MRGPRX4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0718279-B1 | Process for the preparation of o-substituted benzoylcyanides | BASF AG (DE) | 1997-09-24 | — | — | EP | disclosed |
| EP-0718279-A1 | Process for the preparation of o-substituted benzoylcyanides | BASF AKTIENGESELLSCHAFT (DE) | 1996-06-26 | — | — | EP | disclosed |
| US-5221762-A | Reacting a phenol with benzolactone compound; then phosgene or thionyl chloride; esterification with alcohol | BASF AKTIENGESELLSCHAFT (DE) | 1993-06-22 | — | — | US | disclosed |
| EP-0493711-A1 | Process for the preparation of E-oximethers from phenylglyoxylic acid esters | BASF Aktiengesellschaft (DE) | 1992-07-08 | — | — | EP | disclosed |