Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 9/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.53 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.52 |
| ▸ | ANO2 | Q9NQ90 | 1/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8783048 | 0.88 | MRGPRX4 (0.50) | MRGPRX4MAPTFFAR1FFAR4TP53 | |
| SCHEMBL8783051 | 0.86 | MRGPRX4 (0.60) | MRGPRX4PTGDR2MEN1KMT2ATP53 | |
| SCHEMBL8783044 | 0.86 | MRGPRX4 (0.80) | MRGPRX4TP53HTT | |
| SCHEMBL8782203 | 0.85 | MRGPRX4 (0.52) | MRGPRX4MAPTPTGDR2FFAR1FFAR4 | |
| SCHEMBL8782034 | 0.85 | MRGPRX4 (0.55) | MRGPRX4MAPTANO1PTGDR2ANO2 | |
| SCHEMBL7965281 | 0.84 | TP53 (0.54) | MRGPRX4PTGDR2MEN1KMT2ATP53 | |
| SCHEMBL8782968 | 0.84 | FFAR4 (0.54) | MRGPRX4FFAR1FFAR4TP53HTT | |
| SCHEMBL8590480 | 0.84 | SCN4A (0.55) | MRGPRX4MAPTANO1PTGDR2ANO2 | |
| SCHEMBL8617226 | 0.83 | HIF1A (0.53) | MRGPRX4MAPTANO1PTGDR2ANO2 | |
| SCHEMBL8617228 | 0.83 | HIF1A (0.53) | MRGPRX4MAPTANO1PTGDR2ANO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0718279-B1 | Process for the preparation of o-substituted benzoylcyanides | BASF AG (DE) | 1997-09-24 | — | — | EP | disclosed |
| EP-0718279-A1 | Process for the preparation of o-substituted benzoylcyanides | BASF AKTIENGESELLSCHAFT (DE) | 1996-06-26 | — | — | EP | disclosed |
| US-5221762-A | Reacting a phenol with benzolactone compound; then phosgene or thionyl chloride; esterification with alcohol | BASF AKTIENGESELLSCHAFT (DE) | 1993-06-22 | — | — | US | disclosed |
| EP-0493711-A1 | Process for the preparation of E-oximethers from phenylglyoxylic acid esters | BASF Aktiengesellschaft (DE) | 1992-07-08 | — | — | EP | disclosed |