Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24322112 | 0.82 | SMN1; SMN2 (0.45) | SMN1; SMN2POLBPKMMAPTNAPRT | |
| SCHEMBL29515045 | 0.82 | SMN1; SMN2 (0.45) | SMN1; SMN2POLBPKMMAPTNAPRT | |
| SCHEMBL1983742 | 0.79 | SMN1; SMN2 (0.40) | SMN1; SMN2POLBPKMMAPTCYP2D6 | |
| SCHEMBL25940246 | 0.78 | CYP3A4 (0.40) | SMN1; SMN2NAPRTCYP2D6CYP3A4SLC6A2 | |
| SCHEMBL2326586 | 0.71 | SMN1; SMN2 (0.47) | SMN1; SMN2POLBPKMMAPTNAPRT | |
| SCHEMBL1856161 | 0.71 | CYP3A4 (0.42) | SMN1; SMN2POLBPKMNAPRTCYP2D6 | |
| SCHEMBL29515201 | 0.71 | CYP3A4 (0.42) | SMN1; SMN2POLBPKMNAPRTCYP2D6 | |
| SCHEMBL594060 | 0.71 | CYP3A4 (0.42) | SMN1; SMN2POLBPKMNAPRTCYP2D6 | |
| SCHEMBL23474122 | 0.70 | CYP3A4 (0.44) | SMN1; SMN2POLBNAPRTCYP2D6CYP3A4 | |
| SCHEMBL22562669 | 0.69 | CYP3A4 (0.43) | SMN1; SMN2POLBNAPRTCYP2D6CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0398293-B1 | Pyridazinone derivatives and compositions for controlling and/or preventing insect pests | NISSAN CHEMICAL IND LTD (JP) | 1997-08-13 | — | — | EP | disclosed |
| US-5278163-A | Insecticides, pesticides | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1994-01-11 | — | — | US | disclosed |
| EP-0398293-A1 | Pyridazinone derivatives and compositions for controlling and/or preventing insect pests | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1990-11-22 | — | — | EP | disclosed |