Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF4EBP1 | Q13541 | 3/20 | 0.34 |
| ▸ | CD38 | P28907 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | GUCY1A1 | Q02108 | 4/20 | 0.34 |
| ▸ | GUCY1B1 | Q02153 | 4/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9207419 | 0.93 | CD38 (0.34) | EIF4EBP1CD38KMT2AKDM4EALDH1A1 | |
| SCHEMBL6950342 | 0.92 | KMT2A (0.37) | EIF4EBP1CD38KMT2AKDM4EALDH1A1 | |
| SCHEMBL9206247 | 0.92 | KMT2A (0.34) | EIF4EBP1CD38KMT2AKDM4EALDH1A1 | |
| SCHEMBL9201272 | 0.91 | CYP3A4 (0.33) | CD38KMT2AKDM4EALDH1A1MEN1 | |
| SCHEMBL9200498 | 0.90 | EIF4EBP1 (0.33) | EIF4EBP1KMT2AKDM4EALDH1A1MEN1 | |
| SCHEMBL9207426 | 0.89 | EIF4EBP1 (0.34) | EIF4EBP1KMT2AKDM4EALDH1A1MEN1 | |
| SCHEMBL9206253 | 0.88 | EIF4EBP1 (0.34) | EIF4EBP1KMT2AKDM4EALDH1A1MEN1 | |
| SCHEMBL8783227 | 0.87 | CD38 (0.40) | CD38KMT2AKDM4EALDH1A1MEN1 | |
| SCHEMBL9200500 | 0.85 | EIF4EBP1 (0.34) | EIF4EBP1KMT2APDE10A | |
| SCHEMBL6949348 | 0.83 | KMT2A (0.36) | KMT2AKDM4EALDH1A1MEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0758328-A1 | ANTI-CANCER COMPOUNDS CONTAINING CYCLOPENTAQUINAZOLINE RING | BTG INTERNATIONAL LIMITED (GB) | 1997-02-19 | — | — | EP | disclosed |
| WO-1995030673-A1 | ANTI-CANCER COMPOUNDS CONTAINING CYCLOPENTAQUINAZOLINE RING | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1995-11-16 | — | — | WO | disclosed |