Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 19/20 | 0.70 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8786836 | 0.88 | TACR1 (0.58) | TACR1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL8786435 | 0.82 | TACR1 (0.73) | TACR1 | |
| SCHEMBL8786531 | 0.81 | TACR1 (0.76) | TACR1 | |
| SCHEMBL15678903 | 0.79 | TACR1 (1.00) | TACR1 | |
| SCHEMBL14463974 | 0.79 | TACR1 (1.00) | TACR1 | |
| SCHEMBL8788726 | 0.78 | TACR1 (0.71) | TACR1 | |
| SCHEMBL5317173 | 0.77 | TACR1 (0.62) | TACR1MEN1KMT2A | |
| SCHEMBL8785732 | 0.77 | TACR1 (1.00) | TACR1 | |
| SCHEMBL8786133 | 0.76 | TACR1 (0.70) | TACR1 | |
| SCHEMBL5315215 | 0.76 | TACR1 (1.00) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0585913-B1 | Condensed heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1997-12-29 | — | — | EP | disclosed |
| US-5700810-A | Condensed heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-12-23 | — | — | US | disclosed |
| US-5482967-A | LOWERING CHOLESTEROL | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-01-09 | — | — | US | disclosed |
| EP-0585913-A2 | Condensed heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-03-09 | — | — | EP | disclosed |