Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 3/20 | 0.60 |
| ▸ | HTR2C | P28335 | 4/20 | 0.46 |
| ▸ | HTR2B | P41595 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TLR2 | O60603 | 2/20 | 0.41 |
| ▸ | TERT | O14746 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.40 |
| ▸ | F2R | P25116 | 4/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.40 |
| ▸ | CTSC | P53634 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29758903 | 1.00 | PRCP (0.60) | PRCPHTR2CHTR2BKDM4ETLR2 | |
| SCHEMBL27702100 | 0.95 | PRCP (0.55) | PRCPHTR2CHTR2BKDM4ETLR2 | |
| SCHEMBL1705576 | 0.90 | PRCP (0.66) | PRCPHTR2CHTR2BKDM4ETLR2 | |
| SCHEMBL15329272 | 0.87 | PRCP (0.70) | PRCPHTR2CHTR2BKDM4ETLR2 | |
| SCHEMBL11587198 | 0.85 | PRCP (0.59) | PRCPHTR2CHTR2BKDM4ETLR2 | |
| Hydrochloric Acid SCHEMBL11585126 | 0.83 | PRCP (0.57) | PRCPHTR2CHTR2BKDM4ETLR2 | |
| SCHEMBL4578345 | 0.82 | PRCP (0.64) | PRCPHTR2CHTR2BKDM4ETLR2 | |
| SCHEMBL5097625 | 0.82 | PRCP (0.64) | PRCPHTR2CHTR2BKDM4ETLR2 | |
| SCHEMBL21582234 | 0.82 | PRCP (0.64) | PRCPHTR2CHTR2BKDM4ETLR2 | |
| SCHEMBL4578350 | 0.82 | PRCP (0.64) | PRCPHTR2CHTR2BKDM4ETLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0626942-B1 | BICYCLO[2.2.2.]OCTANE DERIVATIVES AS CHOLESTOCYSTOKININ INHIBITORS | BLACK JAMES FOUNDATION (GB) | 1997-04-23 | — | — | EP | disclosed |
| US-5514683-A | LIGANDS FKOR CHOLECYSTOKININ OR GASTRIN RECEPTORS | JAMES BLACK FOUNDATION LIMITED (GB) | 1996-05-07 | — | — | US | disclosed |
| EP-0626942-A1 | BICYCLO 2.2.2.]OCTANE DERIVATIVES AS CHOLESTOCYSTOKININ INHIBITORS. | BLACK JAMES FOUNDATION (GB) | 1994-12-07 | — | — | EP | disclosed |
| WO-1993016982-A1 | BICYCLO[2.2.2.]OCTANE DERIVATIVES AS CHOLESTOCYSTOKININ INHIBITORS | JAMES BLACK FOUNDATION LIMITED (GB) | 1993-09-02 | — | — | WO | disclosed |