Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.78 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.78 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.78 |
| ▸ | CA12 | O43570 | 6/20 | 0.72 |
| ▸ | CA2 | P00918 | 6/20 | 0.72 |
| ▸ | CA9 | Q16790 | 5/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.67 |
| ▸ | MPO | P05164 | 8/20 | 0.64 |
| ▸ | PKM | P14618 | 1/20 | 0.62 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.60 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL460754 | 0.88 | TSHR (1.00) | TSHRCYP2D6HIF1ACA12CA2 | |
| SCHEMBL2794849 | 0.84 | CA12 (1.00) | TSHRCYP2D6HIF1ACA12CA2 | |
| SCHEMBL12083246 | 0.84 | TSHR (0.82) | TSHRCYP2D6HIF1ACA12CA2 | |
| SCHEMBL31532322 | 0.84 | CA12 (1.00) | TSHRCYP2D6HIF1ACA12CA2 | |
| SCHEMBL1436928 | 0.83 | CA12 (0.80) | TSHRCYP2D6HIF1ACA12CA2 | |
| SCHEMBL29566183 | 0.83 | CA12 (0.80) | TSHRCYP2D6HIF1ACA12CA2 | |
| SCHEMBL7930135 | 0.82 | TSHR (0.78) | TSHRCYP2D6HIF1ACA12CA2 | |
| SCHEMBL30586211 | 0.82 | CA12 (0.95) | TSHRCYP2D6HIF1ACA12CA2 | |
| SCHEMBL30586212 | 0.82 | CA12 (0.95) | TSHRCYP2D6HIF1ACA12CA2 | |
| SCHEMBL30586214 | 0.82 | CA12 (0.95) | TSHRCYP2D6HIF1ACA12CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143363-B2 | Polymerizable composition | HENKEL AG & CO. KGAA (DE) | 2012-03-27 | — | — | US | disclosed |
| EP-2297222-B1 | POLYMERIZABLE COMPOSITION CONTAINING INORGANIC PARTICLES HAVING AN ORGANIC SHELL | HENKEL AG & CO KGAA (DE) | 2011-11-02 | — | — | EP | disclosed |
| US-20110105680-A1 | Polymerizable Composition | HENKEL AG & CO. KGAA (DE) | 2011-05-05 | — | — | US | disclosed |
| WO-2010003800-A2 | POLYMERIZABLE COMPOSITION | HENKEL AG & CO. KGAA (DE) | 2010-01-14 | — | — | WO | disclosed |
| WO-2010003940-A1 | POLYMERIZABLE COMPOSITION CONTAINING INORGANIC PARTICLES HAVING AN ORGANIC SHELL | HENKEL AG & CO. KGAA (DE) | 2010-01-14 | — | — | WO | disclosed |