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SCHEMBL8789783

SCHEMBL8789783

CN1C(C)(C)CC(CCCCNc2nc(NCCCN(CCN(CCCNc3nc(NCCCCC4CC(C)(C)N(C)C(C)(C)C4)nc(OC4CC(C)(C)N(C)C(C)(C)C4)n3)c3nc(NCCCCC4CC(C)(C)N(C)C(C)(C)C4)nc(OC4CC(C)(C)N(C)C(C)(C)C4)n3)c3nc(NCCCCC4CC(C)(C)N(C)C(C)(C)C4)nc(OC4CC(C)(C)N(C)C(C)(C)C4)n3)nc(OC3CC(C)(C)N(C)C(C)(C)C3)n2)CC1(C)C

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8788779 0.96 SMN1; SMN2 (0.30) SMN1; SMN2
SCHEMBL8894313 0.91 — —
SCHEMBL8788556 0.91 — —
SCHEMBL8789360 0.90 — —
SCHEMBL8789750 0.90 SMN1; SMN2 (0.32) SMN1; SMN2
SCHEMBL4280278 0.90 SMN1; SMN2 (0.33) SMN1; SMN2
SCHEMBL8788874 0.89 SMN1; SMN2 (0.32) SMN1; SMN2
SCHEMBL8790002 0.87 — —
SCHEMBL8790164 0.87 SMN1; SMN2 (0.31) SMN1; SMN2
SCHEMBL8790199 0.86 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0601978-A1 Process for the preparation of 2,2,6,6-tetramethyl-4-piperidyloxy-1,3,5-triazines with two or more triazine rings CIBA-GEIGY AG (CH) 1994-06-15 — — EP claimed
US-5652364-A REACTION OF CYANURIC CHLORIDE WITH ALKANOLS OR ALKOXIDES FOLLOWED BY REACTION WITH TETRAMETHYL-4-PIPERIDINOLS CIBA-GEIGY CORPORATION (US) 1997-07-29 — — US disclosed
EP-0601978-B1 Process for the preparation of 2,2,6,6-tetramethyl-4-piperidyloxy-1,3,5-triazines with two or more triazine rings CIBA GEIGY AG (CH) 1997-05-02 — — EP disclosed
EP-0601978-A1 Process for the preparation of 2,2,6,6-tetramethyl-4-piperidyloxy-1,3,5-triazines with two or more triazine rings CIBA-GEIGY AG (CH) 1994-06-15 — — EP disclosed