Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.33 |
| ▸ | CETP | P11597 | 3/20 | 0.31 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | RXRB | P28702 | 1/20 | 0.31 |
| ▸ | RXRG | P48443 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29572668 | 0.84 | CETP (0.38) | TSHRMEN1KMT2AMRGPRX4CETP | |
| SCHEMBL8791075 | 0.84 | TSHR (0.37) | SRCTSHRMEN1KMT2AMRGPRX4 | |
| SCHEMBL1462554 | 0.84 | CETP (0.38) | TSHRMEN1KMT2AMRGPRX4CETP | |
| SCHEMBL18114054 | 0.83 | MEN1 (0.39) | TSHRMEN1KMT2A | |
| SCHEMBL12744552 | 0.83 | CETP (0.38) | TSHRMEN1KMT2AMRGPRX4CETP | |
| SCHEMBL30460515 | 0.82 | SMPD1 (0.37) | TSHRMEN1KMT2AMRGPRX4CETP | |
| SCHEMBL23066880 | 0.79 | CETP (0.34) | TSHRMEN1KMT2AMRGPRX4CETP | |
| SCHEMBL8790985 | 0.79 | BTN3A1 (0.33) | TSHRMEN1KMT2AMRGPRX4 | |
| SCHEMBL29868024 | 0.79 | BTN3A1 (0.33) | TSHRMEN1KMT2AMRGPRX4 | |
| SCHEMBL22905924 | 0.78 | CETP (0.34) | MEN1KMT2AMRGPRX4CETPKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0558959-B1 | Phosphonooxy and carbonate derivatives of taxol | BRISTOL MYERS SQUIBB CO (US) | 1997-04-16 | — | — | EP | disclosed |
| US-H1487-H | Antitumor agents; treatment of ovarian, breast and other cancers | BRISTOL-MYERS SQUIBB COMPANY (US) | 1995-09-05 | — | — | US | disclosed |
| US-5272171-A | Phosphonooxy and carbonate derivatives of taxol | BRISTOL-MYERS SQUIBB COMPANY (US) | 1993-12-21 | — | — | US | disclosed |
| EP-0569281-A1 | Benzoate derivatives of taxol | Bristol-Myers Squibb Company (US) | 1993-11-10 | — | — | EP | disclosed |
| EP-0558959-A1 | Phosphonooxy and carbonate derivatives of taxol | Bristol-Myers Squibb Company (US) | 1993-09-08 | — | — | EP | disclosed |