Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 20/20 | 0.73 |
| ▸ | DHFR | P00374 | 1/20 | 0.58 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8792221 | 0.88 | DHODH (0.70) | DHODHDHFRALKBH5 | |
| SCHEMBL8792827 | 0.87 | DHODH (0.71) | DHODHDHFRALKBH5 | |
| SCHEMBL9502210 | 0.85 | DHODH (1.00) | DHODHDHFRALKBH5 | |
| SCHEMBL8792342 | 0.84 | DHODH (0.65) | DHODHDHFRALKBH5 | |
| SCHEMBL8732559 | 0.84 | DHODH (1.00) | DHODHDHFRALKBH5 | |
| SCHEMBL8792348 | 0.83 | DHODH (0.64) | DHODHDHFRALKBH5 | |
| SCHEMBL8794638 | 0.82 | DHODH (0.57) | DHODHDHFRALKBH5 | |
| SCHEMBL8792419 | 0.82 | DHODH (1.00) | DHODHDHFRALKBH5 | |
| SCHEMBL3894369 | 0.82 | DHODH (0.95) | DHODHDHFRALKBH5 | |
| SCHEMBL5908719 | 0.81 | DHODH (0.95) | DHODHDHFRALKBH5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0379145-B1 | Substituted quinolinecarboxylic acids | AMERICAN CYANAMID CO (US) | 1997-05-07 | — | — | EP | claimed |
| EP-0379145-A2 | Substituted quinolinecarboxylic acids | AMERICAN CYANAMID COMPANY (US) | 1990-07-25 | — | — | EP | claimed |
| EP-0648768-B1 | Preparation of 3-dihaloacetyl oxazolidines | MONSANTO CO (US) | 1997-11-26 | — | — | EP | disclosed |
| EP-0379145-B1 | Substituted quinolinecarboxylic acids | AMERICAN CYANAMID CO (US) | 1997-05-07 | — | — | EP | disclosed |
| US-5428172-A | Preparation of 3-dihaloacetyl oxazolidines | MONSANTO COMPANY (US) | 1995-06-27 | — | — | US | disclosed |
| EP-0648768-A1 | Preparation of 3-dihaloacetyl oxazolidines | MONSANTO COMPANY (US) | 1995-04-19 | — | — | EP | disclosed |
| EP-0379145-A2 | Substituted quinolinecarboxylic acids | AMERICAN CYANAMID COMPANY (US) | 1990-07-25 | — | — | EP | disclosed |