Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 6/20 | 0.65 |
| ▸ | SRD5A2 | P31213 | 6/20 | 0.65 |
| ▸ | CNR2 | P34972 | 6/20 | 0.52 |
| ▸ | CNR1 | P21554 | 6/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3405579 | 0.97 | SRD5A1 (0.69) | SRD5A1SRD5A2CNR2CNR1KMT2A | |
| Hydrochloric Acid SCHEMBL8793984 | 0.97 | SRD5A1 (0.68) | SRD5A1SRD5A2CNR2CNR1KMT2A | |
| SCHEMBL8792776 | 0.94 | SRD5A1 (0.61) | SRD5A1SRD5A2CNR2CNR1KMT2A | |
| SCHEMBL8793729 | 0.90 | CNR1 (0.56) | SRD5A1SRD5A2CNR2CNR1CREBBP | |
| SCHEMBL8792553 | 0.89 | SRD5A1 (0.72) | SRD5A1SRD5A2CNR2CNR1KMT2A | |
| SCHEMBL8792253 | 0.88 | SRD5A1 (0.56) | SRD5A1SRD5A2CNR2CNR1 | |
| SCHEMBL8794327 | 0.87 | CNR1 (0.56) | SRD5A1SRD5A2CNR2CNR1CREBBP | |
| SCHEMBL9337697 | 0.85 | CNR2 (0.53) | SRD5A1SRD5A2CNR2CNR1KMT2A | |
| SCHEMBL8793423 | 0.85 | CREBBP (0.52) | SRD5A1SRD5A2CNR2CNR1CREBBP | |
| SCHEMBL27314275 | 0.84 | SRD5A1 (0.74) | SRD5A1SRD5A2CNR2CNR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0458207-B1 | Indole derivatives | FUJISAWA PHARMACEUTICAL CO (JP) | 1997-03-26 | — | — | EP | disclosed |
| US-5312829-A | Testosterone 5alpha-reductase inhibitors | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-05-17 | — | — | US | disclosed |
| US-5212320-A | Enzyme inhibitors | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-05-18 | — | — | US | disclosed |
| EP-0458207-A2 | Indole derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-11-27 | — | — | EP | disclosed |