⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8792568 | 0.92 | — | — | |
| SCHEMBL8794677 | 0.90 | — | — | |
| SCHEMBL8793266 | 0.88 | — | — | |
| SCHEMBL9326149 | 0.87 | — | — | |
| SCHEMBL8793254 | 0.85 | — | — | |
| SCHEMBL9423029 | 0.85 | — | — | |
| SCHEMBL8793979 | 0.85 | — | — | |
| SCHEMBL8794406 | 0.83 | — | — | |
| SCHEMBL8794615 | 0.80 | — | — | |
| SCHEMBL9422858 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0452151-B1 | Substituted aromatic sulfonamides as antiglaucoma agents | MERCK & CO INC (US) | 1997-07-16 | — | — | EP | disclosed |
| US-5334591-A | Useful in the treatment of ocular hypertension and glaucoma | MERCK & CO., INC. (US) | 1994-08-02 | — | — | US | disclosed |
| US-5308863-A | Carbonic anhydrase inhibitors | MERCK & CO., INC. (US) | 1994-05-03 | — | — | US | disclosed |