Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | TTK | P33981 | 1/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.40 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | S100A4 | P26447 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.36 |
| ▸ | MEN1 | O00255 | 6/20 | 0.36 |
| ▸ | RAB9A | P51151 | 5/20 | 0.36 |
| ▸ | NPC1 | O15118 | 5/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CDC25B | P30305 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3274379 | 0.83 | MAPT (0.42) | MAPTTP53MAPK10LMNAMAPK1 | |
| SCHEMBL5969253 | 0.81 | MAPT (0.41) | MAPTTP53MAPK10LMNAMAPK1 | |
| SCHEMBL8346760 | 0.80 | MAPT (0.40) | MAPTTP53MAPK10LMNAMAPK1 | |
| SCHEMBL1197981 | 0.80 | MAPT (0.40) | MAPTTP53MAPK10LMNAMAPK1 | |
| SCHEMBL28965546 | 0.76 | MEN1 (0.33) | MAPTTP53MAPK10LMNAMAPK1 | |
| SCHEMBL15226169 | 0.76 | MAPK10 (0.38) | MAPTTP53MAPK10LMNAMAPK1 | |
| SCHEMBL4238705 | 0.76 | MAPK10 (0.38) | MAPTTP53MAPK10LMNAMAPK1 | |
| SCHEMBL6688204 | 0.72 | MAPT (0.45) | MAPTTP53MAPK10LMNAMAPK1 | |
| SCHEMBL11592156 | 0.70 | MAPT (0.44) | MAPTTP53MAPK10LMNAMAPK1 | |
| SCHEMBL8040477 | 0.69 | MAPT (0.42) | MAPTTP53MAPK10LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0444944-B1 | Synthesis and elucidation of azamitosene and iminoazamitosene | RES CORP TECHNOLOGIES INC (US) | 1997-09-24 | — | — | EP | disclosed |
| EP-0444944-A2 | Synthesis and elucidation of azamitosene and iminoazamitosene | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1991-09-04 | — | — | EP | disclosed |
| US-5015742-A | Antitumor agents | ARIZONA BOARD OF REGENTS (US) | 1991-05-14 | — | — | US | disclosed |