Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8796484 | 0.88 | GAA (0.39) | SMN1; SMN2LPAR1ALDH1A1KMT2AMEN1 | |
| SCHEMBL8796439 | 0.86 | NPC1 (0.34) | SMN1; SMN2LPAR1ALDH1A1KMT2AMEN1 | |
| SCHEMBL8796388 | 0.85 | HPGD (0.35) | ALDH1A1KMT2AMEN1LMNAHPGD | |
| SCHEMBL7960049 | 0.85 | LPAR1 (0.33) | SMN1; SMN2LPAR1ALDH1A1KMT2AMEN1 | |
| SCHEMBL7959967 | 0.85 | LPAR1 (0.39) | SMN1; SMN2LPAR1ALDH1A1KMT2AMEN1 | |
| SCHEMBL8796214 | 0.84 | LPAR1 (0.35) | SMN1; SMN2LPAR1ALDH1A1KMT2AMEN1 | |
| SCHEMBL8796943 | 0.83 | LPAR1 (0.38) | SMN1; SMN2LPAR1ALDH1A1NPC1RAB9A | |
| SCHEMBL8796360 | 0.83 | MEN1 (0.35) | LPAR1KMT2AMEN1HTTNPC1 | |
| SCHEMBL8796492 | 0.78 | NPC1 (0.37) | LPAR1ALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL7949850 | 0.77 | LPAR1 (0.41) | LPAR1ALDH1A1KMT2AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0629604-B1 | Alicyclic phospholipase A2 inhibitors | BRISTOL MYERS SQUIBB CO (US) | 1997-04-16 | — | — | EP | claimed |
| EP-0754175-A1 | ALKOXY-ALKYL-SUBSTITUTED 1-H-3-ARYL-PYRROLIDINE-2,4-DIONES USED AS HERBICIDES AND PESTICIDES | BAYER AG (DE) | 1997-01-22 | — | — | EP | disclosed |