Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 16/20 | 0.56 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.47 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.47 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.47 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.47 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.47 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.47 |
| ▸ | GPR65 | Q8IYL9 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | MRGPRX1 | Q96LB2 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9321931 | 0.94 | TACR1 (0.60) | TACR1CACNA1FCHRM5CACNA1DCACNA1S | |
| SCHEMBL8795072 | 0.89 | TACR1 (0.54) | TACR1CACNA1FCHRM5CACNA1DCACNA1S | |
| SCHEMBL8796571 | 0.89 | TACR1 (0.54) | TACR1CACNA1FCHRM5CACNA1DCACNA1S | |
| SCHEMBL8795961 | 0.86 | TACR1 (0.52) | TACR1CACNA1FCHRM5CACNA1DCACNA1S | |
| SCHEMBL9154749 | 0.86 | TACR1 (0.55) | TACR1CACNA1FCHRM5CACNA1DCACNA1S | |
| SCHEMBL8795934 | 0.84 | TACR1 (0.49) | TACR1CACNA1FCHRM5CACNA1DCACNA1S | |
| SCHEMBL8795448 | 0.84 | TACR1 (0.52) | TACR1CACNA1FCHRM5CACNA1DCACNA1S | |
| SCHEMBL5077903 | 0.83 | TACR1 (0.67) | TACR1CACNA1FCHRM5CACNA1DCACNA1S | |
| SCHEMBL27705860 | 0.83 | TACR1 (0.67) | TACR1CACNA1FCHRM5CACNA1DCACNA1S | |
| SCHEMBL9323013 | 0.83 | TACR1 (0.67) | TACR1CACNA1FCHRM5CACNA1DCACNA1S |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0591333-B1 | AZANORBORNANE DERIVATIVES | PFIZER (US) | 1997-03-05 | — | — | EP | disclosed |
| WO-1993000330-A2 | AZANORBORNANE DERIVATIVES | PFIZER INC. (US) | 1993-01-07 | — | — | WO | disclosed |