Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTH1R | Q03431 | 12/20 | 0.51 |
| ▸ | SLC6A9 | P48067 | 3/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL849372 | 0.89 | PTH1R (0.49) | PTH1RSLC6A9 | |
| SCHEMBL848105 | 0.86 | PTH1R (0.69) | PTH1R | |
| SCHEMBL879689 | 0.85 | PTH1R (0.50) | PTH1RSLC6A9 | |
| SCHEMBL879608 | 0.84 | PTH1R (0.49) | PTH1RSLC6A9 | |
| SCHEMBL846716 | 0.83 | PTH1R (0.48) | PTH1RSLC6A9 | |
| SCHEMBL16302128 | 0.83 | PTH1R (0.47) | PTH1RSLC6A9 | |
| SCHEMBL847202 | 0.82 | PTH1R (0.47) | PTH1RSLC6A9 | |
| SCHEMBL16302171 | 0.80 | PTH1R (0.46) | PTH1RSLC6A9 | |
| SCHEMBL849803 | 0.80 | PTH1R (0.46) | PTH1RSLC6A9 | |
| SCHEMBL13064502 | 0.79 | PTH1R (0.47) | PTH1RSLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2433940-A1 | SPIROIMIDAZOLONE DERIVATIVE | Chugai Seiyaku Kabushiki Kaisha (JP) | 2012-03-28 | — | — | EP | disclosed |