Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 6/20 | 0.56 |
| ▸ | SRD5A2 | P31213 | 6/20 | 0.56 |
| ▸ | CNR2 | P34972 | 6/20 | 0.43 |
| ▸ | CNR1 | P21554 | 5/20 | 0.43 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9604317 | 0.93 | SRD5A1 (0.59) | SRD5A1SRD5A2CNR2CNR1CREBBP | |
| SCHEMBL9334540 | 0.82 | SRD5A1 (0.70) | SRD5A1SRD5A2CNR2CNR1CREBBP | |
| SCHEMBL9334460 | 0.81 | SRD5A1 (0.72) | SRD5A1SRD5A2CNR2CNR1 | |
| SCHEMBL9337583 | 0.79 | SRD5A1 (0.44) | SRD5A1SRD5A2CNR2CNR1 | |
| SCHEMBL5701972 | 0.78 | SRD5A1 (0.74) | SRD5A1SRD5A2CNR2CNR1CREBBP | |
| SCHEMBL9334476 | 0.78 | SRD5A1 (0.79) | SRD5A1SRD5A2CNR2CNR1CREBBP | |
| Hydrochloric Acid SCHEMBL9337443 | 0.77 | SRD5A1 (0.70) | SRD5A1SRD5A2CNR2CNR1CREBBP | |
| SCHEMBL27314275 | 0.76 | SRD5A1 (0.74) | SRD5A1SRD5A2CNR2CNR1CREBBP | |
| SCHEMBL8792810 | 0.76 | SRD5A1 (0.76) | SRD5A1SRD5A2CNR2CNR1CREBBP | |
| SCHEMBL9334537 | 0.75 | SRD5A1 (0.67) | SRD5A1SRD5A2CNR2CNR1CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0458207-B1 | Indole derivatives | FUJISAWA PHARMACEUTICAL CO (JP) | 1997-03-26 | — | — | EP | disclosed |
| US-5312829-A | Testosterone 5alpha-reductase inhibitors | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-05-17 | — | — | US | disclosed |
| US-5212320-A | Enzyme inhibitors | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-05-18 | — | — | US | disclosed |
| EP-0458207-A2 | Indole derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-11-27 | — | — | EP | disclosed |