Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTH1R | Q03431 | 6/20 | 0.51 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL847186 | 0.83 | PTH1R (0.48) | PTH1RCALCRLACHE | |
| SCHEMBL847187 | 0.83 | PTH1R (0.48) | PTH1RCALCRLACHE | |
| SCHEMBL13552188 | 0.78 | PTH1R (0.47) | PTH1RCALCRL | |
| SCHEMBL849378 | 0.76 | PTH1R (0.49) | PTH1RCALCRLEPHX2 | |
| SCHEMBL849251 | 0.76 | PTH1R (0.57) | PTH1RCALCRLEPHX2 | |
| SCHEMBL847240 | 0.76 | PTH1R (0.70) | PTH1RCALCRL | |
| SCHEMBL13385961 | 0.74 | PTH1R (0.52) | PTH1RCALCRL | |
| SCHEMBL849883 | 0.74 | PTH1R (0.52) | PTH1RCALCRL | |
| SCHEMBL848256 | 0.73 | PTH1R (0.43) | PTH1RCALCRL | |
| SCHEMBL848255 | 0.73 | PTH1R (0.43) | PTH1RCALCRL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2433940-A1 | SPIROIMIDAZOLONE DERIVATIVE | Chugai Seiyaku Kabushiki Kaisha (JP) | 2012-03-28 | — | — | EP | disclosed |