Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.52 |
| ▸ | PIM1 | P11309 | 4/20 | 0.52 |
| ▸ | PIM2 | Q9P1W9 | 4/20 | 0.52 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 2/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8796684 | 1.00 | HPGD (0.52) | HPGDPIM1PIM2AKR1B1NPC1 | |
| SCHEMBL8797673 | 0.93 | HPGD (0.52) | HPGDPIM1PIM2AKR1B1NPC1 | |
| SCHEMBL8797670 | 0.93 | HPGD (0.52) | HPGDPIM1PIM2AKR1B1NPC1 | |
| SCHEMBL8796699 | 0.91 | CSNK2A2 (0.51) | HPGDPIM1PIM2MAOB | |
| SCHEMBL8797738 | 0.91 | HPGD (0.52) | HPGDPIM1PIM2HRH3CISD1 | |
| SCHEMBL8797741 | 0.91 | HPGD (0.52) | HPGDPIM1PIM2HRH3CISD1 | |
| SCHEMBL8796772 | 0.87 | MGAM (0.58) | HPGDPIM1PIM2POLBHRH3 | |
| SCHEMBL7454718 | 0.87 | MGAM (0.58) | HPGDPIM1PIM2POLBHRH3 | |
| SCHEMBL8803534 | 0.84 | MAOB (0.48) | MAOB | |
| SCHEMBL8797677 | 0.84 | CSNK2A2 (0.51) | HPGDPIM1PIM2AKR1B1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0787727-A1 | Benzoazine derivative or salt thereof and pharmaceutical composition comprising the same | SS Pharmaceutical Co., Ltd. (JP) | 1997-08-06 | — | — | EP | disclosed |