Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.60 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | F2R | P25116 | 1/20 | 0.51 |
| ▸ | PARP1 | P09874 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.49 |
| ▸ | MGLL | Q99685 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6212581 | 0.92 | MAPK1 (0.61) | CYP4F2CYP4A11MAPK1LMNAMAPT | |
| SCHEMBL8867339 | 0.89 | MAPK1 (0.58) | CYP4F2CYP4A11MAPK1LMNAMAPT | |
| SCHEMBL8867305 | 0.86 | MAPT (0.61) | MAPK1LMNAMAPTHSD17B10ALDH1A1 | |
| SCHEMBL4197894 | 0.85 | MAPK1 (0.64) | MAPK1LMNAMAPTHSD17B10ALDH1A1 | |
| SCHEMBL6188909 | 0.85 | MAPT (0.58) | MAPK1LMNAMAPTHSD17B10ALDH1A1 | |
| SCHEMBL12569392 | 0.84 | MAPK1 (0.59) | MAPK1LMNAMAPTHSD17B10ALDH1A1 | |
| SCHEMBL6193765 | 0.84 | MAPK1 (0.53) | MAPK1LMNAMAPTHSD17B10ALDH1A1 | |
| SCHEMBL21349100 | 0.84 | MAPK1 (0.66) | MAPK1LMNAMAPTHSD17B10ALDH1A1 | |
| Hydrochloric Acid SCHEMBL3051482 | 0.83 | MAPK1 (0.58) | MAPK1LMNAMAPTHSD17B10ALDH1A1 | |
| SCHEMBL6404645 | 0.82 | NPC1 (0.54) | CYP4F2CYP4A11LMNAHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686484-A | ANTHELMINTICS, ACARICIDES, INSECTICIDES | SANKYO CO., LTD. (JP) | 1997-11-11 | — | — | US | disclosed |
| EP-0759913-A1 | AROMATIC AMINE SUBSTITUTED BRIDGED NITROGEN AND SULFUR DONOR ATOM LIGANDS FOR IMAGING | NEORX CORPORATION (US) | 1997-03-05 | — | — | EP | disclosed |
| WO-1995032192-A1 | AROMATIC AMINE SUBSTITUTED BRIDGED NITROGEN AND SULFUR DONOR ATOM LIGANDS FOR IMAGING | NEORX CORPORATION (US) | 1995-11-30 | — | — | WO | disclosed |