Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SETD7 | Q8WTS6 | 3/20 | 0.61 |
| ▸ | HRH1 | P35367 | 4/20 | 0.54 |
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.54 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.54 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.54 |
| ▸ | HTR1A | P08908 | 1/20 | 0.54 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.54 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.54 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.54 |
| ▸ | DRD2 | P14416 | 1/20 | 0.54 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.54 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.54 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.54 |
| ▸ | DRD1 | P21728 | 1/20 | 0.54 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7217786 | 0.99 | SETD7 (0.59) | SETD7HRH1TSHRTP53CYP2D6 | |
| SCHEMBL9035852 | 0.88 | SETD7 (0.68) | SETD7HRH1TSHRTP53CYP2D6 | |
| Hydrochloric Acid SCHEMBL7213868 | 0.87 | SETD7 (0.66) | SETD7HRH1TSHRTP53CYP2D6 | |
| SCHEMBL8797112 | 0.85 | SETD7 (0.57) | SETD7HRH1TSHRTP53CYP2D6 | |
| SCHEMBL9034769 | 0.84 | SETD7 (0.62) | SETD7HRH1TSHRTP53CYP2D6 | |
| SCHEMBL9215703 | 0.84 | FNTA (0.63) | SETD7HRH1TSHRCHRM2HTR1A | |
| SCHEMBL9036519 | 0.84 | SETD7 (0.67) | SETD7HRH1TSHRTP53CYP2D6 | |
| Hydrochloric Acid SCHEMBL7217793 | 0.84 | SETD7 (0.56) | SETD7HRH1TSHRTP53CYP2D6 | |
| SCHEMBL9034527 | 0.83 | SETD7 (0.61) | SETD7HRH1TSHRTP53CYP2D6 | |
| Hydrochloric Acid SCHEMBL7218936 | 0.83 | SETD7 (0.65) | SETD7HRH1TSHRTP53CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0371805-B1 | Piperidine derivatives and hypotensives containing the same | AJINOMOTO KK (JP) | 1996-06-26 | — | — | EP | claimed |
| EP-0371805-A2 | Piperidine derivatives and hypotensives containing the same | AJINOMOTO CO., INC. (JP) | 1990-06-06 | — | — | EP | claimed |
| EP-0642514-B1 | BRIDGED BIS-ARYL CARBINOL DERIVATIVES, COMPOSITIONS AND METHODS OF USE | SCHERING CORP (US) | 1997-05-21 | — | — | EP | disclosed |
| US-5561117-A | TREATING ASTHMA, ALLERGIES AND INFLAMMATION | SCHERING CORPORATION (US) | 1996-10-01 | — | — | US | disclosed |
| EP-0535152-B1 | Bis-benzo or benzopyrido cyclo hepta piperidene, piperidylene and piperazine compounds as PAF antagonists and compositions thereof. | SCHERING CORP (US) | 1995-08-09 | — | — | EP | disclosed |
| US-5430032-A | Treating asthma, allergy, inflammation | SCHERING CORPORATION (US) | 1995-07-04 | — | — | US | disclosed |
| US-5422351-A | Antiallergens; antiinflammatory agents | SCHERING CORPORATION (US) | 1995-06-06 | — | — | US | disclosed |
| EP-0642514-A1 | BRIDGED BIS-ARYL CARBINOL DERIVATIVES, COMPOSITIONS AND METHODS OF USE. | SCHERING CORP (US) | 1995-03-15 | — | — | EP | disclosed |
| EP-0595989-A1 | BENZOPYRIDO PIPERYLIDENE COMPOUNDS, COMPOSITIONS, METHODS OF MANUFACTURE AND METHODS OF USE | SCHERING CORPORATION (US) | 1994-05-11 | — | — | EP | disclosed |
| WO-1993020080-A1 | BRIDGED BIS-ARYL CARBINOL DERIVATIVES, COMPOSITIONS AND METHODS OF USE | SCHERING CORPORATION (US) | 1993-10-14 | — | — | WO | disclosed |
| WO-1993002081-A1 | NOVEL BENZOPYRIDO PIPERYLIDENE COMPOUNDS, COMPOSITIONS, METHODS OF MANUFACTURE AND METHODS OF USE | SCHERING CORPORATION (US) | 1993-02-04 | — | — | WO | disclosed |
| EP-0524784-A1 | Benzopyrido piperidylidene compounds as PAF antagonists | SCHERING CORPORATION (US) | 1993-01-27 | — | — | EP | disclosed |
| WO-1992000293-A1 | BIS-BENZO OR BENZOPYRIDO CYCLO HEPTA PIPERIDENE, PIPERIDYLIDENE AND PIPERAZINE COMPOUNDS AND COMPOSITIONS | SCHERING CORPORATION (US) | 1992-01-09 | — | — | WO | disclosed |