Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTH1R | Q03431 | 10/20 | 0.54 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16104695 | 0.90 | PTH1R (0.53) | PTH1RCALCRLTACR1 | |
| SCHEMBL846985 | 0.89 | PTH1R (0.52) | PTH1RCALCRLTACR1 | |
| SCHEMBL16357745 | 0.88 | PTH1R (0.57) | PTH1RCALCRLTACR1 | |
| SCHEMBL849061 | 0.86 | PTH1R (0.51) | PTH1RCALCRLTACR1 | |
| SCHEMBL847063 | 0.85 | PTH1R (0.56) | PTH1RCALCRLTACR1 | |
| SCHEMBL848464 | 0.84 | PTH1R (0.55) | PTH1RCALCRLTACR1 | |
| SCHEMBL847044 | 0.84 | PTH1R (0.52) | PTH1RCALCRLTACR1 | |
| SCHEMBL847043 | 0.84 | PTH1R (0.52) | PTH1RCALCRLTACR1 | |
| SCHEMBL850855 | 0.84 | PTH1R (0.51) | PTH1RCALCRLTACR1 | |
| SCHEMBL847870 | 0.82 | PTH1R (0.56) | PTH1RCALCRLTACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2433940-A1 | SPIROIMIDAZOLONE DERIVATIVE | Chugai Seiyaku Kabushiki Kaisha (JP) | 2012-03-28 | — | — | EP | disclosed |