Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 12/20 | 0.47 |
| ▸ | PPARG | P37231 | 8/20 | 0.47 |
| ▸ | PPARA | Q07869 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8797423 | 0.89 | HRH3 (0.50) | HRH3FFAR1PPARGPPARACYP3A4 | |
| SCHEMBL8797128 | 0.89 | HRH3 (0.50) | HRH3FFAR1PPARGPPARACYP3A4 | |
| SCHEMBL8797127 | 0.89 | HRH3 (0.50) | HRH3FFAR1PPARGPPARACYP3A4 | |
| SCHEMBL8797686 | 0.89 | PPARG (0.51) | HRH3FFAR1PPARGPPARACYP3A4 | |
| SCHEMBL8796790 | 0.89 | FFAR1 (0.57) | HRH3FFAR1PPARGPPARACYP3A4 | |
| SCHEMBL8796966 | 0.89 | FFAR1 (0.53) | HRH3FFAR1PPARGPPARACYP3A4 | |
| SCHEMBL8796796 | 0.89 | HRH3 (0.49) | HRH3FFAR1PPARGPPARACYP3A4 | |
| SCHEMBL8797732 | 0.88 | HRH3 (0.52) | HRH3FFAR1PPARGPPARACYP3A4 | |
| SCHEMBL8802229 | 0.88 | HRH3 (0.48) | HRH3FFAR1PPARGPPARACYP3A4 | |
| SCHEMBL8797017 | 0.87 | HRH3 (0.52) | HRH3FFAR1PPARGPPARACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0787727-A1 | Benzoazine derivative or salt thereof and pharmaceutical composition comprising the same | SS Pharmaceutical Co., Ltd. (JP) | 1997-08-06 | — | — | EP | disclosed |