⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8317612 | 0.86 | — | — | |
| SCHEMBL8314304 | 0.86 | — | — | |
| SCHEMBL7411838 | 0.85 | — | — | |
| SCHEMBL7416313 | 0.85 | — | — | |
| SCHEMBL8314326 | 0.84 | — | — | |
| SCHEMBL8314874 | 0.84 | — | — | |
| SCHEMBL7413525 | 0.83 | — | — | |
| SCHEMBL8316449 | 0.82 | — | — | |
| SCHEMBL7414305 | 0.81 | — | — | |
| SCHEMBL7409610 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0752991-A1 | INDENO[1,2-e]PYRAZINE-4-ONES, PREPARATION THEREOF AND DRUGS CONTAINING SAME | Aventis Pharma S.A. (FR) | 1997-01-15 | — | — | EP | disclosed |
| WO-1995026349-A1 | INDENO[1,2-e]PYRAZINE-4-ONES, PREPARATION THEREOF AND DRUGS CONTAINING SAME | RHONE-POULENC RORER S.A. (FR) | 1995-10-05 | — | — | WO | disclosed |