Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.58 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.42 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 3/20 | 0.41 |
| ▸ | CES1 | P23141 | 3/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8798824 | 0.83 | TSHR (0.44) | ACE2CA1MAPTCES2CES1 | |
| SCHEMBL16213113 | 0.82 | ACE2 (0.66) | ACE2FFAR1FFAR4GPR84MAPT | |
| SCHEMBL2222385 | 0.82 | ACE2 (0.66) | ACE2FFAR1FFAR4GPR84MAPT | |
| SCHEMBL1134744 | 0.82 | ACE2 (0.66) | ACE2FFAR1FFAR4GPR84MAPT | |
| SCHEMBL13746761 | 0.82 | ACE2 (0.66) | ACE2FFAR1FFAR4GPR84MAPT | |
| SCHEMBL25275005 | 0.82 | ACE2 (0.66) | ACE2FFAR1FFAR4GPR84MAPT | |
| SCHEMBL3626201 | 0.82 | ACE2 (0.66) | ACE2FFAR1FFAR4GPR84MAPT | |
| SCHEMBL8036038 | 0.82 | ACE2 (0.66) | ACE2FFAR1FFAR4GPR84MAPT | |
| SCHEMBL8812279 | 0.82 | ACE2 (0.60) | ACE2FFAR1FFAR4GPR84CA1 | |
| SCHEMBL2545350 | 0.82 | ACE2 (0.66) | ACE2FFAR1FFAR4GPR84MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5650430-A | Radicicol derivatives, their preparation and their anti-tumor activity | SANKYO COMPANY, LIMITED (JP) | 1997-07-22 | — | — | US | disclosed |
| EP-0460950-B1 | Radicicol derivatives, their preparation and their anti-tumour activity | SANKYO CO (JP) | 1997-03-05 | — | — | EP | disclosed |
| US-5597846-A | ESTERS OF RADICICOL | SANKYO COMPANY, LIMITED (JP) | 1997-01-28 | — | — | US | disclosed |
| WO-1991018905-A1 | RADICICOL DERIVATIVES, THEIR PREPARATION AND THEIR ANTI-TUMOR ACTIVITY | SANKYO COMPANY LIMITED (JP) | 1991-12-12 | — | — | WO | disclosed |
| EP-0460950-A1 | Radicicol derivatives, their preparation and their anti-tumour activity | Sankyo Company Limited (JP) | 1991-12-11 | — | — | EP | disclosed |