Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.56 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | SCN4A | P35499 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | NPY1R | P25929 | 1/20 | 0.49 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL773201 | 1.00 | CYP1A2 (0.63) | CYP1A2KMT2ASMN1; SMN2KCNH2CACNA1G | |
| SCHEMBL8798100 | 1.00 | CYP1A2 (0.63) | CYP1A2KMT2ASMN1; SMN2KCNH2CACNA1G | |
| SCHEMBL11127254 | 0.90 | SMN1; SMN2 (0.61) | CYP1A2KMT2ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL15450588 | 0.89 | CYP1A2 (0.60) | CYP1A2KMT2ASMN1; SMN2KCNH2CACNA1G | |
| SCHEMBL9922436 | 0.85 | CYP1A2 (0.59) | CYP1A2KMT2ASMN1; SMN2KCNH2CACNA1G | |
| SCHEMBL9922127 | 0.85 | CYP1A2 (0.59) | CYP1A2KMT2ASMN1; SMN2KCNH2CACNA1G | |
| SCHEMBL11140249 | 0.83 | CYP1A2 (0.66) | CYP1A2KMT2AKCNH2CACNA1GMAPK1 | |
| SCHEMBL20883372 | 0.83 | KMT2A (0.55) | CYP1A2KMT2ASMN1; SMN2KCNH2CACNA1G | |
| SCHEMBL6074194 | 0.82 | PTGS1 (0.57) | KMT2ASMN1; SMN2KCNH2MAPTTSHR | |
| SCHEMBL1496562 | 0.82 | CYP1A2 (0.60) | CYP1A2KMT2ASMN1; SMN2KCNH2CACNA1G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0702015-B1 | Bicyclic oxazole and thiazole substituted ethers | CIBA GEIGY AG (CH) | 1997-09-24 | — | — | EP | disclosed |
| EP-0702015-A1 | Bicyclic oxazole and thiazole substituted ethers | SANDOZ LTD. (CH) | 1996-03-20 | — | — | EP | disclosed |