Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.67 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | DHODH | Q02127 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | TYK2 | P29597 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ALPL | P05186 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6807189 | 0.88 | KMT2A (0.76) | KMT2AL3MBTL1SORT1DHODHLMNA | |
| SCHEMBL7493834 | 0.87 | KMT2A (0.65) | KMT2AL3MBTL1SORT1HPGDDHODH | |
| SCHEMBL16674460 | 0.85 | KMT2A (0.63) | KMT2AL3MBTL1HPGDTYK2NPC1 | |
| SCHEMBL14398931 | 0.85 | DHODH (0.56) | KMT2AL3MBTL1SORT1DHODHLMNA | |
| SCHEMBL3820618 | 0.83 | HTT (0.66) | KMT2AL3MBTL1HPGDDHODHGAA | |
| SCHEMBL8604699 | 0.82 | DHODH (0.64) | KMT2AL3MBTL1DHODHLMNAGAA | |
| SCHEMBL7553677 | 0.82 | DHODH (0.56) | KMT2AL3MBTL1SORT1DHODHGAA | |
| SCHEMBL18640822 | 0.82 | GRM4 (0.58) | KMT2AL3MBTL1HPGDDHODHLMNA | |
| SCHEMBL7497000 | 0.82 | DHODH (0.56) | KMT2AL3MBTL1DHODHLMNAGAA | |
| SCHEMBL18640842 | 0.81 | KMT2A (0.64) | KMT2ADHODHGAANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0804438-A1 | TRICYCLIC BENZAZEPINE VASOPRESSIN ANTAGONISTS | American Cyanamid Company (US) | 1997-11-05 | — | — | EP | disclosed |