Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| L-706125 SCHEMBL8800303 | 1.00 | TACR1 (1.00) | TACR1 | |
| L-706125 SCHEMBL8799997 | 1.00 | TACR1 (1.00) | TACR1 | |
| L-706125 SCHEMBL8799993 | 1.00 | TACR1 (1.00) | TACR1 | |
| L-706125 SCHEMBL8800931 | 0.99 | TACR1 (0.98) | TACR1 | |
| L-706125 SCHEMBL8800934 | 0.99 | TACR1 (0.98) | TACR1 | |
| L-706125 SCHEMBL8800016 | 0.99 | TACR1 (0.98) | TACR1 | |
| L-706125 SCHEMBL8800012 | 0.99 | TACR1 (0.98) | TACR1 | |
| L-706125 SCHEMBL8800711 | 0.94 | TACR1 (0.89) | TACR1 | |
| L-706125 SCHEMBL8800578 | 0.94 | TACR1 (0.89) | TACR1 | |
| L-706125 SCHEMBL8800584 | 0.94 | TACR1 (0.89) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0499313-B1 | Azabicyclic compounds, pharmaceutical compositions containing them and their use in therapy | MERCK SHARP & DOHME (GB) | 1997-06-11 | — | — | EP | claimed |
| EP-0499313-A1 | Azabicyclic compounds, pharmaceutical compositions containing them and their use in therapy | MERCK SHARP & DOHME LTD. (GB) | 1992-08-19 | — | — | EP | claimed |