Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2858162 | 0.87 | TACR1 (0.55) | TACR1 | |
| SCHEMBL2785002 | 0.87 | TACR1 (0.55) | TACR1 | |
| SCHEMBL2858767 | 0.87 | TACR1 (0.55) | TACR1 | |
| SCHEMBL2858768 | 0.87 | TACR1 (0.55) | TACR1 | |
| SCHEMBL8800656 | 0.87 | TACR1 (0.55) | TACR1 | |
| SCHEMBL699568 | 0.76 | CHRNA7 (0.49) | TACR1 | |
| SCHEMBL8801190 | 0.74 | TACR1 (0.80) | TACR1 | |
| Hydrochloric Acid SCHEMBL8801141 | 0.73 | TACR1 (0.78) | TACR1 | |
| Hydrochloric Acid SCHEMBL8801149 | 0.73 | TACR1 (0.78) | TACR1 | |
| Hydrochloric Acid SCHEMBL8801143 | 0.73 | TACR1 (0.78) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0499313-B1 | Azabicyclic compounds, pharmaceutical compositions containing them and their use in therapy | MERCK SHARP & DOHME (GB) | 1997-06-11 | — | — | EP | disclosed |
| US-5242930-A | AZABICYCLIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE IN THERAPY | MERCK SHARP & DOHME LTD. | 1993-09-07 | — | — | US | disclosed |
| EP-0499313-A1 | Azabicyclic compounds, pharmaceutical compositions containing them and their use in therapy | MERCK SHARP & DOHME LTD. (GB) | 1992-08-19 | — | — | EP | disclosed |