SCHEMBL8801129

SCHEMBL8801129

O=C(O)CSc1cc(-n2nc3n(c2=O)CCCC3)c(F)cc1Cl

nearest known ligand 0.46

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 20/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10386332 0.87 DHODH (0.47) DHODH
SCHEMBL8807437 0.82 DHODH (0.47) DHODH
SCHEMBL4390450 0.81 DHODH (0.51) DHODH
SCHEMBL9664832 0.77 DHODH (0.47) DHODH
SCHEMBL4072262 0.76 DHODH (0.54) DHODH
SCHEMBL9664791 0.75 DHODH (0.51) DHODH
SCHEMBL20112128 0.75 DHODH (0.54) DHODH
SCHEMBL9663252 0.75 DHODH (0.45) DHODH
SCHEMBL9665722 0.75 DHODH (0.51) DHODH
SCHEMBL10386333 0.74 DHODH (0.50) DHODH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0690844-B1 PROCESS TO PREPARE HERBICIDAL BICYCLIC TRIAZOLES DU PONT (US) 1997-10-22 EP claimed
WO-1994022828-A1 PROCESS TO PREPARE HERBICIDAL BICYCLIC TRIAZOLES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1994-10-13 WO claimed
EP-0690844-B1 PROCESS TO PREPARE HERBICIDAL BICYCLIC TRIAZOLES DU PONT (US) 1997-10-22 EP disclosed
WO-1994022828-A1 PROCESS TO PREPARE HERBICIDAL BICYCLIC TRIAZOLES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1994-10-13 WO disclosed