SCHEMBL8801741

SCHEMBL8801741

COC(=O)c1sc(C(=O)O)cc1OC

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.42
KMT2A Q03164 3/20 0.42
TSHR P16473 1/20 0.42
HSD17B10 Q99714 1/20 0.42
ALDH1A1 P00352 5/20 0.41
KDM4E B2RXH2 5/20 0.41
DAO P14920 2/20 0.41
MEN1 O00255 2/20 0.41
HPGD P15428 1/20 0.41
SHMT2 P34897 1/20 0.40
CA12 O43570 2/20 0.40
CA1 P00915 2/20 0.40
CA2 P00918 2/20 0.40
CA4 P22748 2/20 0.40
CA6 P23280 2/20 0.40
CA7 P43166 2/20 0.40
CA9 Q16790 2/20 0.40
CA14 Q9ULX7 2/20 0.40
GLA P06280 1/20 0.40
CA3 P07451 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6179820 0.89 DAO (0.44) MAPTKMT2AALDH1A1KDM4EDAO
SCHEMBL13992671 0.87 MAPT (0.41) MAPTKMT2ATSHRHSD17B10ALDH1A1
SCHEMBL8928555 0.79 MAPT (0.46) MAPTKMT2ATSHRHSD17B10ALDH1A1
SCHEMBL12272115 0.79 MAPT (0.57) MAPTKMT2ATSHRHSD17B10ALDH1A1
SCHEMBL577651 0.79 MAPT (0.44) MAPTKMT2ATSHRHSD17B10ALDH1A1
SCHEMBL14419258 0.78 GAA (0.44) MAPTKMT2ATSHRHSD17B10ALDH1A1
SCHEMBL12272132 0.78 DAO (0.55) MAPTKMT2ATSHRHSD17B10ALDH1A1
SCHEMBL12523092 0.78 KDM4E (0.53) MAPTKMT2ATSHRHSD17B10ALDH1A1
SCHEMBL17203200 0.78 MAPT (0.42) MAPTKMT2ATSHRHSD17B10ALDH1A1
SCHEMBL1371646 0.78 KMT2A (0.42) MAPTKMT2ATSHRHSD17B10ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0794950-A1 DERIVATIVES OF ANTHRANILIC ACID USEFUL AS FUNGICIDES AgrEvo UK Limited (GB) 1997-09-17 EP disclosed
WO-1996016954-A1 DERIVATIVES OF ANTHRANILIC ACID USEFUL AS FUNGICIDES AGREVO UK LIMITED (GB) 1996-06-06 WO disclosed