Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 1/20 | 0.58 |
| ▸ | FNTB | P49356 | 1/20 | 0.58 |
| ▸ | SCN9A | Q15858 | 7/20 | 0.44 |
| ▸ | CCKAR | P32238 | 1/20 | 0.43 |
| ▸ | CCKBR | P32239 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.40 |
| ▸ | KLK7 | P49862 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8801152 | 0.90 | FNTA (0.56) | FNTAFNTBSCN9ACCKARCCKBR | |
| SCHEMBL29450579 | 0.88 | FNTA (0.74) | FNTAFNTBCCKARCCKBRHDAC3 | |
| SCHEMBL8801920 | 0.86 | FNTA (0.51) | FNTAFNTBSCN9ACCKARCCKBR | |
| SCHEMBL8801733 | 0.85 | FNTA (0.53) | FNTAFNTBCCKARCCKBRHDAC3 | |
| SCHEMBL8674098 | 0.84 | FNTA (0.46) | FNTAFNTBSCN9ACCKARCCKBR | |
| SCHEMBL8801159 | 0.84 | FNTA (0.60) | FNTAFNTBCCKARCCKBRHDAC3 | |
| SCHEMBL8800669 | 0.83 | FNTA (0.54) | FNTAFNTBSCN9ACCKARCCKBR | |
| SCHEMBL8801102 | 0.83 | FNTA (0.52) | FNTAFNTBCCKARCCKBRHDAC3 | |
| SCHEMBL8801416 | 0.82 | FNTA (0.64) | FNTAFNTBCCKARCCKBRHDAC3 | |
| SCHEMBL29520033 | 0.82 | FNTA (0.64) | FNTAFNTBCCKARCCKBRHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0763537-A2 | Non-peptidyl Ras farnesyl transferase inhibitors | GENENTECH, INC. (US) | 1997-03-19 | — | — | EP | disclosed |
| US-5532359-A | FUNGICIDES | GENENTECH, INC. (US) | 1996-07-02 | — | — | US | disclosed |
| EP-0698015-A1 | PREPARATION OF N-CYANODITHIOIMINO-CARBONATES AND 3-MERCAPTO-5-AMINO-1H-1,2,4-TRIAZOLE | GENENTECH, INC. (US) | 1996-02-28 | — | — | EP | disclosed |
| WO-1994026723-A2 | ras FARNESYL TRANSFERASE INHIBITORS | GENENTECH, INC. (US) | 1994-11-24 | — | — | WO | disclosed |