Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 5/20 | 0.47 |
| ▸ | CCKAR | P32238 | 3/20 | 0.47 |
| ▸ | FNTA | P49354 | 1/20 | 0.43 |
| ▸ | FNTB | P49356 | 1/20 | 0.43 |
| ▸ | OXTR | P30559 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8803112 | 0.79 | FNTA (0.45) | CCKBRCCKARFNTAFNTBOXTR | |
| SCHEMBL8801155 | 0.77 | FNTA (0.51) | CCKBRCCKARFNTAFNTBOXTR | |
| SCHEMBL8802185 | 0.73 | FNTA (0.59) | CCKBRCCKARFNTAFNTBOXTR | |
| SCHEMBL8801333 | 0.73 | FNTA (0.52) | CCKBRCCKARFNTAFNTBOXTR | |
| SCHEMBL8801920 | 0.73 | FNTA (0.51) | CCKBRCCKARFNTAFNTBOXTR | |
| SCHEMBL15221506 | 0.72 | FNTA (0.56) | CCKBRCCKARFNTAFNTBOXTR | |
| SCHEMBL8801152 | 0.70 | FNTA (0.56) | CCKBRCCKARFNTAFNTBOXTR | |
| SCHEMBL8940414 | 0.69 | FNTA (0.54) | CCKBRCCKARFNTAFNTBOXTR | |
| SCHEMBL29450579 | 0.68 | FNTA (0.74) | CCKBRCCKARFNTAFNTBOXTR | |
| SCHEMBL8801488 | 0.68 | FNTA (0.51) | CCKBRCCKARFNTAFNTBOXTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0763537-A2 | Non-peptidyl Ras farnesyl transferase inhibitors | GENENTECH, INC. (US) | 1997-03-19 | — | — | EP | disclosed |
| EP-0698015-A1 | PREPARATION OF N-CYANODITHIOIMINO-CARBONATES AND 3-MERCAPTO-5-AMINO-1H-1,2,4-TRIAZOLE | GENENTECH, INC. (US) | 1996-02-28 | — | — | EP | disclosed |
| WO-1994026723-A2 | ras FARNESYL TRANSFERASE INHIBITORS | GENENTECH, INC. (US) | 1994-11-24 | — | — | WO | disclosed |